منابع مشابه
Marbofloxacin
IN THE TITLE COMPOUND, [SYSTEMATIC NAME: 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazin-1-yl)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carb-oxy-lic acid], C(17)H(19)FN(4)O(4), the carbonyl and carboxyl groups are coplanar with the quinoline ring, making a dihedral angle of 2.39 (2)°. The piperazine ring adopts a chair conformation and the oxadiazinane ring displays an envelope con...
متن کاملIntegration of Pharmacokinetic and Pharmacodynamic Indices of Marbofloxacin in Turkeys Running title: PK-PD of marbofloxacin in turkeys
1. Department of Veterinary Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands 2. Department of Pharmacology, Physiology and Chemistry, Faculty of Veterinary Medicine, Trakia University, Bulgaria 3. Department of Microbiology, Infectious and Parasitic Diseases, Section of Microbiology, Faculty of Veterinary Medicine, Trakia University, Bul...
متن کاملField Experience with Intravenous Marbofloxacin against Acute Mastitis
Mastitis is by far the most common and most costly disease in milk production in industrialised countries. Costs are related to loss in milk quality, decreased milk production related to subclinical mastitis, discarded milk, replacement cows, cost of treatment and labour costs [1]. This disease is the most frequent reason for the use of antimicrobials in dairy cows [2]. It can be classified int...
متن کاملIntegration of pharmacokinetic and pharmacodynamic indices of marbofloxacin in turkeys.
Fluoroquinolones are extensively used in the treatment of systemic bacterial infections in poultry, including systemic Escherichia coli bacillosis, which is a common disease in turkey flocks. Marbofloxacin has been licensed for use in various mammalian species, but not as yet for turkeys, although its kinetic properties distinguish it from other fluoroquinolones. For example, the longer half-li...
متن کاملPK-PD Analysis of Marbofloxacin against Streptococcus suis in Pigs
Marbofloxacin is a fluoroquinolone antibiotic and highly effective treatment for respiratory diseases. Here we aimed to evaluate the ex vivo activity of marbofloxacin against Streptococcus suis in pig serum, as well as the optimal dosages scheme for avoiding the fluoroquinolone resistance development. A single dose of 8 mg/kg body weight (bw) was administrated orally to healthy pigs and serum s...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2012
ISSN: 1600-5368
DOI: 10.1107/s1600536812009312